BHF Oxbridge Centre of Regenerative Medicine (CRM) has a pump-priming budget to support innovative ideas that need to produce preliminary data before submitting a project grant application to an external funding body.
Since 2014 there have been four rounds of pump-priming funding and the Centre has allocated nearly £700,000 of its budget. Decisions are always taken after external peer review of the applications.
There are no plans for any further calls for new pump-priming proposals.
Details of the projects funded under CRM1 and CRM2 are listed below.
| Name | Location | Title | Award | Call |
|---|
|
|
|
|
2019 |
| Nicola Smart |
Oxford |
Asymmetric cell division in the epicardium: a novel target for regeneration? |
£41,700 |
|
| Tilly Mommersteeg |
Oxford |
Comparing heart regeneration versus scarring on single cell level |
£30,568 |
|
| Shoumo Bhattacharya |
Oxford |
Characterisation of the chemokine network in myocardial infarction |
£19,668 |
|
| Martin Bennett |
Cambridge |
Rejuvenating aged intra-myocardial arteries after myocardial infarction |
£46,700 |
|
| Helle Jorgensen |
Cambridge |
Transcriptional profiling of single cells from human arteries to identify primed/progenitor cell populations |
£25,310 |
|
| Rebecca Richardson |
Bristol |
Validation of cardiomyocyte specific gene expression in macrophages after cardiac injury |
£43,954 |
|
| Kim Mace |
Manchester |
Reversing chronic inflammation through modulation of reactive oxygen species |
£15,000 |
|
| Jurgen Schneider |
Leeds |
Development of advanced MR imaging techniques for the regenerating mouse heart |
£49,988 |
|
|
|
|
|
2016 |
| Shoumo Bhattacharya |
|
Targeting cardiac inflammation in post-infarction myocardial injury using novel chemokine-ligand traps derived from tick saliva |
£20,474 |
|
| Nicola Smart |
|
Generating new transgenic models to study the coronary vasculature |
£24,595 |
|
| Paul Martin |
|
Development of novel zebrafish models to analyse endogenous extracellular vesicle trafficking during the cardiac injury response and subsequent regeneration |
£28,118 |
|
| Helle Jorgensen |
|
Investigation of vascular smooth muscle cell heterogeneity |
£22,910 |
|
|
|
|
|
2015 |
| Jurgen Schneider |
Oxford |
Tracking stem cells in the living myocardium using 19F-MRI - a new paradigm for optimising preclinical studies
|
£29,995 |
|
| Tilly Mommersteeg |
Oxford |
Heart regeneration: is it in the blood?
|
£29,960 |
|
| Nicola Smart |
Oxford |
Sulfatases: novel targets for enhancing regeneration by epicardium-derived cells?
|
£17,472 |
|
| Shankar Srinivas |
Oxford |
Characterising the initiation of coordinated calcium transients in the developing heart
|
£27,617 |
|
| Paul Martin |
Bristol |
Development of novel software for live imaging inflammatory cell interactions in the beating heart
|
£16,281 |
|
| Helle Jorgensen |
Cambridge |
Developing a Crispr/Cas9-mediated system for regulation of local chromatin configuration
|
£23,678 |
|
| Amer Rana |
Cambridge |
Modelling cardiomyocyte biology in pulmonary arterial hypertension using induced pluripotent stem cells
|
£23,100 |
|
|
|
|
|
2014 |
| Shoumo Bhattacharya |
Oxford |
Targeting RASopathic fibrosis signalling pathways using monobodies |
£17,900 |
|
| David Greaves |
Oxford |
CD68-Luciferase reporter mice for in vivo imaging of monocyte recruitment in repair |
£26,000 |
|
| Nicola Smart |
Oxford |
SRSF3: a novel splicing regulator of epicardial gene networks? |
£12,738 |
|
| Helle Jorgensen |
Cambridge |
In vivo proliferation of vascular smooth muscle cells |
£22,479 |
|
| Roger Pedersen |
Cambridge |
Generation of human pluripotent stem cell lines capable of reporting cardiac chamber-specific differentiation |
£27,922 |
|
