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BHF Oxbridge Centre of Regenerative Medicine (CRM) has a pump-priming budget to support innovative ideas that need to produce preliminary data before submitting a project grant application to an external funding body.

Since 2014 there have been four rounds of pump-priming funding and the Centre has allocated nearly £700,000 of its budget. Decisions are always taken after external peer review of the applications.

There are no plans for any further calls for new pump-priming proposals.

Details of the projects funded under CRM1 and CRM2 are listed below.

 

NameLocationTitleAwardCall
2019
Nicola Smart Oxford Asymmetric cell division in the epicardium: a novel target for regeneration? £41,700
Tilly Mommersteeg Oxford Comparing heart regeneration versus scarring on single cell level £30,568
Shoumo Bhattacharya Oxford Characterisation of the chemokine network in myocardial infarction £19,668
Martin Bennett Cambridge Rejuvenating aged intra-myocardial arteries after myocardial infarction £46,700
Helle Jorgensen Cambridge Transcriptional profiling of single cells from human arteries to identify primed/progenitor cell populations £25,310
Rebecca Richardson Bristol Validation of cardiomyocyte specific gene expression in macrophages after cardiac injury £43,954
Kim Mace Manchester Reversing chronic inflammation through modulation of reactive oxygen species £15,000
Jurgen Schneider Leeds Development of advanced MR imaging techniques for the regenerating mouse heart £49,988
2016
Shoumo Bhattacharya
Oxford
Targeting cardiac inflammation in post-infarction myocardial injury using novel chemokine-ligand traps derived from tick saliva £20,474
Nicola Smart
Oxford
Generating new transgenic models to study the coronary vasculature £24,595
Paul Martin
Bristol
Development of novel zebrafish models to analyse endogenous extracellular vesicle trafficking during the cardiac injury response and subsequent regeneration £28,118
Helle Jorgensen
Cambridge
Investigation of vascular smooth muscle cell heterogeneity £22,910
2015
Jurgen Schneider Oxford Tracking stem cells in the living myocardium using 19F-MRI - a new paradigm for optimising preclinical studies
£29,995
Tilly Mommersteeg Oxford Heart regeneration: is it in the blood?
£29,960
Nicola Smart Oxford Sulfatases: novel targets for enhancing regeneration by epicardium-derived cells?
£17,472
Shankar Srinivas  Oxford Characterising the initiation of coordinated calcium transients in the developing heart
£27,617
Paul Martin Bristol Development of novel software for live imaging inflammatory cell interactions in the beating heart
£16,281
Helle Jorgensen  Cambridge Developing a Crispr/Cas9-mediated system for regulation of local chromatin  configuration
£23,678
Amer Rana Cambridge Modelling cardiomyocyte biology in pulmonary arterial hypertension using induced pluripotent stem cells
£23,100
2014
Shoumo Bhattacharya Oxford Targeting RASopathic fibrosis signalling pathways using monobodies £17,900
David Greaves Oxford CD68-Luciferase reporter mice for in vivo imaging of monocyte recruitment in repair £26,000
Nicola Smart Oxford SRSF3: a novel splicing regulator of epicardial gene networks? £12,738
Helle Jorgensen Cambridge In vivo proliferation of vascular smooth muscle cells £22,479
Roger Pedersen Cambridge Generation of human pluripotent stem cell lines capable of reporting cardiac chamber-specific differentiation £27,922