BHF Oxbridge Centre of Regenerative Medicine (CRM) has a pump-priming budget to support innovative ideas that need to produce preliminary data before submitting a project grant application to an external funding body.
Since 2014 there have been four rounds of pump-priming funding and the Centre has allocated nearly £700,000 of its budget. Decisions are always taken after external peer review of the applications.
There are no plans for any further calls for new pump-priming proposals.
Details of the projects funded under CRM1 and CRM2 are listed below.
|
Name
|
Location
|
Title
|
Award
|
Call
|
|
|
|
|
2019
|
|
Nicola Smart
|
Oxford
|
Asymmetric cell division in the epicardium: a novel target for regeneration?
|
£41,700
|
|
|
Tilly Mommersteeg
|
Oxford
|
Comparing heart regeneration versus scarring on single cell level
|
£30,568
|
|
|
Shoumo Bhattacharya
|
Oxford
|
Characterisation of the chemokine network in myocardial infarction
|
£19,668
|
|
|
Martin Bennett
|
Cambridge
|
Rejuvenating aged intra-myocardial arteries after myocardial infarction
|
£46,700
|
|
|
Helle Jorgensen
|
Cambridge
|
Transcriptional profiling of single cells from human arteries to identify primed/progenitor cell populations
|
£25,310
|
|
|
Rebecca Richardson
|
Bristol
|
Validation of cardiomyocyte specific gene expression in macrophages after cardiac injury
|
£43,954
|
|
|
Kim Mace
|
Manchester
|
Reversing chronic inflammation through modulation of reactive oxygen species
|
£15,000
|
|
|
Jurgen Schneider
|
Leeds
|
Development of advanced MR imaging techniques for the regenerating mouse heart
|
£49,988
|
|
|
|
|
|
2016
|
|
Shoumo Bhattacharya
|
|
Targeting cardiac inflammation in post-infarction myocardial injury using novel chemokine-ligand traps derived from tick saliva
|
£20,474
|
|
|
Nicola Smart
|
|
Generating new transgenic models to study the coronary vasculature
|
£24,595
|
|
|
Paul Martin
|
|
Development of novel zebrafish models to analyse endogenous extracellular vesicle trafficking during the cardiac injury response and subsequent regeneration
|
£28,118
|
|
|
Helle Jorgensen
|
|
Investigation of vascular smooth muscle cell heterogeneity
|
£22,910
|
|
|
|
|
|
2015
|
|
Jurgen Schneider
|
Oxford
|
Tracking stem cells in the living myocardium using 19F-MRI - a new paradigm for optimising preclinical studies
|
£29,995
|
|
|
Tilly Mommersteeg
|
Oxford
|
Heart regeneration: is it in the blood?
|
£29,960
|
|
|
Nicola Smart
|
Oxford
|
Sulfatases: novel targets for enhancing regeneration by epicardium-derived cells?
|
£17,472
|
|
|
Shankar Srinivas
|
Oxford
|
Characterising the initiation of coordinated calcium transients in the developing heart
|
£27,617
|
|
|
Paul Martin
|
Bristol
|
Development of novel software for live imaging inflammatory cell interactions in the beating heart
|
£16,281
|
|
|
Helle Jorgensen
|
Cambridge
|
Developing a Crispr/Cas9-mediated system for regulation of local chromatin configuration
|
£23,678
|
|
|
Amer Rana
|
Cambridge
|
Modelling cardiomyocyte biology in pulmonary arterial hypertension using induced pluripotent stem cells
|
£23,100
|
|
|
|
|
|
|
2014
|
|
Shoumo Bhattacharya
|
Oxford
|
Targeting RASopathic fibrosis signalling pathways using monobodies
|
£17,900
|
|
|
David Greaves
|
Oxford
|
CD68-Luciferase reporter mice for in vivo imaging of monocyte recruitment in repair
|
£26,000
|
|
|
Nicola Smart
|
Oxford
|
SRSF3: a novel splicing regulator of epicardial gene networks?
|
£12,738
|
|
|
Helle Jorgensen
|
Cambridge
|
In vivo proliferation of vascular smooth muscle cells
|
£22,479
|
|
|
Roger Pedersen
|
Cambridge
|
Generation of human pluripotent stem cell lines capable of reporting cardiac chamber-specific differentiation
|
£27,922
|
|
